Effect of interaction is not clear, use caution. epinephrine and propylhexedrine both decrease sedation. Use Caution/Monitor. oxymorphone increases and epinephrine decreases sedation. Adding plans allows you to compare formulary status to other drugs in the same class. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. amoxapine increases and epinephrine decreases sedation. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (3)epinephrine and pirbuterol both decrease serum potassium. Interaction more likely in certain predisposed pts. epinephrine and metaproterenol both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. prochlorperazine decreases effects of epinephrine by pharmacodynamic antagonism. Monitor Closely (2)labetalol decreases effects of epinephrine by pharmacodynamic antagonism.
Contraindicated. spironolactone increases and epinephrine decreases serum potassium. Avoid or Use Alternate Drug. Modify Therapy/Monitor Closely.iloperidone increases and epinephrine decreases sedation.
quetiapine increases and epinephrine decreases sedation.
Use Caution/Monitor. Effect of interaction is not clear, use caution. Use Caution/Monitor. Effect of interaction is not clear, use caution. Effect of interaction is not clear, use caution. Do not administer these drugs until at least 7 days after each iobenguane dose. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Effect of interaction is not clear, use caution. Use Caution/Monitor.epinephrine and dexmethylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor Closely (1)quazepam increases and epinephrine decreases sedation. Effect of interaction is not clear, use caution. Effect of interaction is not clear, use caution. Use Caution/Monitor. 
In some cases a serious, possibly fatal drug interaction may occur.Caffeine can increase the side effects of this medication. Use Caution/Monitor. Contraindicated.
Monitor Closely (1)ketorolac intranasal increases and epinephrine decreases serum potassium. Monitor Closely (1)epinephrine and metolazone both decrease serum potassium. Use Caution/Monitor. Monitor Closely (3)epinephrine and salmeterol both decrease serum potassium. only.promazine decreases effects of epinephrine by pharmacodynamic antagonism. Use Caution/Monitor. Monitor Closely (1)lornoxicam increases and epinephrine decreases serum potassium. epinephrine and trazodone both increase QTc interval. Contraindicated. Minor/Significance Unknown. Use Caution/Monitor. Use Caution/Monitor. trazodone increases and epinephrine decreases sedation. chlorpromazine decreases effects of epinephrine by pharmacodynamic antagonism. epinephrine and salmeterol both decrease sedation. 
Monitor Closely (1)acemetacin increases and epinephrine decreases serum potassium. Avoid or Use Alternate Drug. Use Caution/Monitor. Use Caution/Monitor.
Use Caution/Monitor.atenolol decreases effects of epinephrine by pharmacodynamic antagonism. Use Caution/Monitor. Monitor Closely (2)epinephrine and lisdexamfetamine both decrease sedation. Do not float the inhaler in water to test if any more drug is left in it. Effect of interaction is not clear, use caution. Avoid or Use Alternate Drug. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)droperidol increases and epinephrine decreases sedation. Use Caution/Monitor.penbutolol decreases effects of epinephrine by pharmacodynamic antagonism. Effect of interaction is not clear, use caution. Effect of interaction is not clear, use caution. Serious - Use Alternative (1)epinephrine will decrease the level or effect of iobenguane I 131 by Other (see comment). Effect of interaction is not clear, use caution. quazepam increases and epinephrine decreases sedation. labetalol increases and epinephrine decreases serum potassium. prochlorperazine increases and epinephrine decreases sedation. Use Caution/Monitor.maprotiline increases effects of epinephrine by unknown mechanism. Effect of interaction is not clear, use caution. Monitor Closely (1)epinephrine and flecainide both increase QTc interval. Use Caution/Monitor. If coadministered, monitor for changes in heart rate, heart rhythm, and blood pressure. Modify Therapy/Monitor Closely. Contraindicated. Be sure to mention any of the following: certain antidepressants such as amitriptyline, amoxapine, clomipramine (Anafranil), desipramine (Norpramin), doxepin (Silenor), imipramine (Tofranil), maprotiline, mirtazapine (Remeron), nortriptyline (Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); antihistamines such as chlorpheniramine (Chlor-Trimeton) and diphenhydramine (Benadryl); beta blockers such as propranolol (Hemangeol, Inderal LA, Innopran XL); digoxin (Lanoxicaps, Lanoxin); diuretics ('water pills'); ergot medications such as dihydroergotamine (D.H.E. eucalyptus increases and epinephrine decreases sedation. Modify Therapy/Monitor Closely. Effect of interaction is not clear, use caution. lornoxicam increases and epinephrine decreases serum potassium. Use Caution/Monitor. epinephrine and amitriptyline both increase QTc interval. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)epinephrine decreases effects of insulin degludec/insulin aspart by pharmacodynamic antagonism. Monitor Closely (1)oxaprozin increases and epinephrine decreases serum potassium. Use Caution/Monitor. Other (see comment). Monitor Closely (2)acebutolol decreases effects of epinephrine by pharmacodynamic antagonism. digoxin increases and epinephrine decreases serum potassium. dopexamine and epinephrine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. epinephrine and erythromycin ethylsuccinate both increase QTc interval. Necrotizing fasciitis and myonecrosis caused by Clostridia (gas gangrene), Reduced blood flow to digits, hands, or feet with accidental injection to those areas, Arrhythmias, including fatal ventricular fibrillation, reported, particularly in patients with underlying cardiac disease or those receiving certain drugs, There are no contraindications for life-threatening situations, Coadministration during genral anesthesia with halogenated hydrocarbons or cyclopropane, Situations where vasopressors may be contraindicated, including thyrotoxicosis, diabetes, Maternal blood pressure in excess of 130/80 mm Hg in hypertension and other cardiovascular disorders, Use caution in patients with cardiac disease, angina (especially with history of CAD) or that are receiving drugs that sensitize the myocardium; treatment may induce cardiac arrhythmias, Pulmonary edema may occur as the result of cardiac stimulation and peripheral constriction, Decreased urine output may occur as the result of renal blood vessel constriction, Use caution in cerebrovascular insufficiency, Use with caution in patients with hypertension, diabetes mellitus, thyroid disease, prostatic hypertrophy, geriatric patients, pregnancy, and previous hospitalization for asthma, Rapid IV administration, although necessary in pulesless arrest, may cause death from cerebrovascular hemorrhage or cardiac arrhythmias, Patients that are sulfite-sensitive, should still be treated during a serious allergic reaction or other emergency even if products available contain sulfites, May cause worsening of symptoms in patients with Parkinson disease, Avoid extravasation; ensure proper needle or catheter placement prior to and during infusion, Correct blood volume depletion before administering any vasopressor, Rare cases of serious skin and soft tissue infections, including necrotizing fasciitis and myonecrosis caused by Clostridia (gas gangrene), reported at injection site following injection for anaphylaxis; to decrease risk, do not inject into buttock; advise patients to seek medical care if they develop signs or symptoms of infection, such as persistent redness, warmth, swelling, or tenderness, at epinephrine injection site; cleansing with alcohol does not kill bacterial spores, and therefore, does not lower risk of infection, Multiple-dose vial not for ophthalmic use; contains chlorobutanol which may be harmful to corneal endothelium, Solutions must be diluted prior to intraocular use; other epinephrine products containing sodium bisulfite have been associated with corneal endothelial damage when used in the eye at undiluted concentrations (1 mg/mL), Autoinjector is to be used in conjunction with immediate medical or hospital care; more than two sequential doses of epinephrine should only be administered under direct medical supervision, During pregnancy, anaphylaxis can be catastrophic and can lead to hypoxic-ischemic encephalopathy and permanent central nervous system damage or death in the mother and, more commonly, in the fetus or neonate, The prevalence of anaphylaxis occurring during pregnancy is reported to be approximately 3 cases per 100,000 deliveries; management of anaphylaxis during pregnancy is similar to management in the general population, Epinephrine is the first line-medication of choice for treatment of anaphylaxis; it should be used in the same manner in pregnant and non-pregnant patients, In conjunction with the administration of epinephrine, the patient should seek immediate medical or hospital care, Hypotension associated with septic shock is a medical emergency in pregnancy which can be fatal if left untreated; delaying treatment in pregnant women with hypotension associated with septic shock may increase risk of maternal and fetal morbidity and mortality, Life-sustaining therapy for pregnant woman should not be withheld due to potential concerns regarding effects of epinephrine on fetus, There is no information regarding presence of epinephrine in human milk or effects on the breastfed infant or on milk production, However, due to poor oral bioavailability and short half-life, epinephrine exposure is expected to be very low in breastfed infant, Epinephrine is first-line medication of choice for treatment of anaphylaxis; it should be used in same manner for anaphylaxis in breastfeeding and non-breastfeeding patients. Avoid or Use Alternate Drug. Use Caution/Monitor. Serious - Use Alternative (1)doxapram increases effects of epinephrine by pharmacodynamic synergism. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. thioridazine increases and epinephrine decreases sedation. Minor (1)noni juice increases and epinephrine decreases serum potassium. Monitor Closely (1)epinephrine and gentamicin both decrease serum potassium. tell your doctor and pharmacist if you are allergic to epinephrine, any other medications, sulfites, or any of the other ingredients in epinephrine injection. epinephrine and dexmethylphenidate both decrease sedation. Use Caution/Monitor. epinephrine and moxifloxacin both increase QTc interval. dobutamine and epinephrine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. What side effects can this medication cause? scullcap increases and epinephrine decreases sedation. Use Caution/Monitor. only. Interaction more likely in certain predisposed pts. Effect of interaction is not clear, use caution. Use Caution/Monitor. Effect of interaction is not clear, use caution. epinephrine and procainamide both increase QTc interval. Use Caution/Monitor. epinephrine and phendimetrazine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Contraindicated. If clinically appropriate, discontinue drugs that compete for NE receptor sites for at least 5 half-lives; may cause false-negative imaging results. Monitor Closely (1)dimenhydrinate increases and epinephrine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor.arformoterol and epinephrine both decrease sedation. levorphanol increases and epinephrine decreases sedation.
dimenhydrinate increases and epinephrine decreases sedation. Hypertension, V tach. Ask your doctor or pharmacist to show you and any of your caregivers who could be injecting the medication how to use the prefilled automatic injection device. This information does not assure that this product is safe, effective, or appropriate for you. Use Caution/Monitor.promethazine, epinephrine. nebivolol increases and epinephrine decreases serum potassium. Use Caution/Monitor. Use Caution/Monitor. If coadministered, monitor for changes in heart rate, heart rhythm, and blood pressure. Avoid or Use Alternate Drug. chloral hydrate increases and epinephrine decreases sedation. Effect of interaction is not clear, use caution. Use Caution/Monitor. Monitor Closely (1)epinephrine and venlafaxine both increase QTc interval. epinephrine and epinephrine racemic both decrease serum potassium. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. epinephrine and dextroamphetamine both decrease sedation. Use Caution/Monitor. Use Caution/Monitor.Minor (1)epinephrine, methyclothiazide. Mechanism: pharmacodynamic antagonism. epinephrine and fluoxetine both increase QTc interval. Use Caution/Monitor. Use Caution/Monitor.albuterol and epinephrine both decrease sedation. epinephrine and carbenoxolone both decrease serum potassium. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Hypotension, tachycardia. Monitor Closely (2)trazodone increases effects of epinephrine by unknown mechanism. Effect of interaction is not clear, use caution. Use Caution/Monitor. Use Caution/Monitor. Do not use the extra liquid; dispose of the remaining liquid and device properly. arformoterol and epinephrine both decrease serum potassium. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely. Use Caution/Monitor. Serious - Use Alternative (1)epinephrine and clarithromycin both increase QTc interval. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Avoid or Use Alternate Drug. Minor/Significance Unknown. dobutamine and epinephrine both decrease sedation. Use Caution/Monitor.epinephrine and phendimetrazine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. trifluoperazine increases and epinephrine decreases sedation. Other (see comment). Effect of interaction is not clear, use caution. Effect of interaction is not clear, use caution. Use Caution/Monitor. albuterol and epinephrine both decrease serum potassium. Use Caution/Monitor. Avoid or Use Alternate Drug. Effect of interaction is not clear, use caution. Effect of interaction is not clear, use caution. epinephrine and levoketoconazole both increase QTc interval. Modify Therapy/Monitor Closely. Mechanism: pharmacodynamic synergism. Mechanism: unknown. Use Caution/Monitor. Avoid or Use Alternate Drug. Sympathomimetics can antagonize the activity of some antihypertensive agents. Additive vasospasm; risk of hypertension. Use Caution/Monitor.epinephrine and epinephrine racemic both decrease sedation. Effect of interaction is not clear, use caution. Indicated to increase mean arterial blood pressure in adults with hypotension associated with septic shock, Recommended dose: 0.05-2 mcg/kg/minute IV infusion; titrate to desired mean arterial pressure (MAP); may adjust dose q10-15 min by 0.05-0.2 mcg/kg/minute to achieve desired blood pressure goal, After hemodynamic stabilization, may wean incrementally q30min over 12-24 hr, Indicated in emergency treatment of allergic reactions (Type I) including anaphylaxis, Unresponsive to atropine or pacing: 2-10 mcg//min by IV infusion or 0.1-0.5 mcg/kg/min (7-35 mcg/min in 70 kg patient); titrate to patient response, Induction and maintenance of mydriasis during intraocular surgery, Use only preservative-free vials without tartaric acid, 0.1 mg/mL solution: 0.01 mg/kg IO/IV q3-5min prn; not to exceed 1 mg/dose, 1 mg/mL solution: 0.1 mg/kg (0.1mL/kg) of endotracheal q3-5min prn; flush each dose with at least 5 mL 0.9% NaCl injection, Neonates (aged <28 days); 0.1 mg/mL solution: 0.01-0.03 mg/kg IVP (0.1-0.3 mL/kg) q3-5min; higher doses not recommended, Neonate IV access not available; 0.1 mg/mL solution: 0.05-0.1 mg/kg endotracheal tube; lower doses not effective; follow each dose with at least 5 mL 0.9% NaCl injection. Monitor Closely (1)oxymetazoline topical and epinephrine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Serious - Use Alternative (1)epinephrine and erythromycin ethylsuccinate both increase QTc interval. Use Caution/Monitor.sotalol decreases effects of epinephrine by pharmacodynamic antagonism. Serious - Use Alternative (1)epinephrine and dosulepin both increase QTc interval. Use Caution/Monitor. Avoid or Use Alternate Drug. Effect of interaction is not clear, use caution. Effect of interaction is not clear, use caution. Avoid or Use Alternate Drug. Effect of interaction is not clear, use caution. tramadol increases and epinephrine decreases sedation. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Effect of interaction is not clear, use caution. Effect of interaction is not clear, use caution. salsalate increases and epinephrine decreases serum potassium. Therefore, coadministration of ozanimod with drugs that can increase norepinephrine or serotonin is not recommended. Use Caution/Monitor. Use Caution/Monitor. Avoid or Use Alternate Drug. Monitor Closely (1)salicylates (non-asa) increases and epinephrine decreases serum potassium. Effect of interaction is not clear, use caution. Monitor Closely (1)epinephrine and ethacrynic acid both decrease serum potassium. Monitor Closely (1)ziconotide increases and epinephrine decreases sedation. opium tincture increases and epinephrine decreases sedation. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. Avoid or Use Alternate Drug. Monitor Closely (2)promazine, epinephrine. Effect of interaction is not clear, use caution. Use Caution/Monitor.epinephrine and dopamine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Effect of interaction is not clear, use caution. Serious - Use Alternative (1)etomidate increases levels of epinephrine by decreasing metabolism. Contraindicated. propofol increases levels of epinephrine by unknown mechanism. ergotamine, epinephrine. Avoid or Use Alternate Drug.
Effect of interaction is not clear, use caution. Use Caution/Monitor.Serious - Use Alternative (2)epinephrine and amoxapine both increase QTc interval. Use Caution/Monitor. tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. Monitor Closely (1)oxazepam increases and epinephrine decreases sedation. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. celiprolol increases and epinephrine decreases serum potassium. Use Caution/Monitor.Minor (1)epinephrine, indapamide. Use Caution/Monitor. Effect of interaction is not clear, use caution. Use Caution/Monitor.dichlorphenamide, epinephrine. Contraindicated (1)epinephrine and procainamide both increase QTc interval. Your list will be saved and can be edited at any time. Avoid or Use Alternate Drug. Epinephrine injection helps to treat serious allergic reactions but does not take the place of medical treatment. Use Caution/Monitor. Epinephrine 1mg/ml Vial 1:1,000 for Anaphylaxis - Each, Check & Inject Epi Kit for NY - Customize, Diphenhydramine HCL, 50mg/ml in 1ml Vial - Each, Albuterol For Inhalation - Unit Dose 0.083% - Individually Foil Packed - 30/Box. Hypokalemia. Contraindicated. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Contraindicated. droperidol increases and epinephrine decreases sedation. Monitor Closely (1)epinephrine and cyclopenthiazide both decrease serum potassium. belladonna and opium increases and epinephrine decreases sedation. Use Caution/Monitor. Monitor Closely (1)epinephrine and pseudoephedrine both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Because the active metabolite of ozanimod inhibits MAO-B in vitro, there is a potential for serious adverse reactions, including hypertensive crisis. Use Caution/Monitor. Monitor Closely (2)nortriptyline increases effects of epinephrine by unknown mechanism. Other (see comment). Use Caution/Monitor.
Use Caution/Monitor. ziprasidone increases and epinephrine decreases sedation. Avoid or Use Alternate Drug. Contraindicated.Monitor Closely (2)sotalol decreases effects of epinephrine by pharmacodynamic antagonism. Bretylium causes an initial norepinephrine release and may enhance catecholamine pressor effects. tell your doctor if you have or have ever had chest pain, irregular heartbeat, high blood pressure, or heart disease; asthma; diabetes; hyperthyroidism (an overactive thyroid); pheochromocytoma (adrenal gland tumor); depression or other mental illness; or Parkinson's disease. Effect of interaction is not clear, use caution. Use Caution/Monitor. Use Caution/Monitor.
Contraindicated (1)epinephrine and disopyramide both increase QTc interval. Monitor Closely (1)epinephrine and serdexmethylphenidate/dexmethylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Effect of interaction is not clear, use caution. desipramine, epinephrine. Monitor Closely (1)tolfenamic acid increases and epinephrine decreases serum potassium. Sympathomimetics increase blood glucose by stimulating alpha and beta receptors; this action results in increased hepatic glucose production, glycogenolysis, and decreased insulin secretion.
Monitor Closely (1)aceclofenac increases and epinephrine decreases serum potassium. ziconotide increases and epinephrine decreases sedation. Also tell your doctor if you are taking a monoamine oxidase inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate) or have stopped taking it within the past two weeks.
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