All-in-one pressure controller and supply powered by battery or line voltage. The Flow EZ can maintain continuous, pulseless flow for days without refilling. With the use of pressure instead of mechanical action, the Flow EZTMgets a responsiveness ten times faster than syringe pumps. 
This technology combines electronic and pneumatic elements engineered together with well established Fluigent regulation algorithms and knowledge. TheLineUpPush-Pullis a standalone controller with the ability to deliverfinely regulated pressureor avacuumthrough a single outlet over the range of-800 to +1000 mbar. When combined with a FLOW UNIT, one can control flow rate directly or deliver dispensed volumes as needed. Control and regulate pressure and flow rate without a PC using the LineUp hardware interface. 1. 
Our innovative pressure-based microfluidic controllers are compatible with lab on a chip device and a wide variety of microfluidic technologies that will allow you to focus on the science, not on the setup. A low response time allows one to quicky execute operations such as stop flow and pressure/flow rate steps. The F-OEM range of modules allows for regulation of vacuum/pressure down to -800 mbar and up to 7 bar, with the possibility to use a push-pull module (-800 / +1 000 mbar). To ensure excellent response time while guaranteeing the best performance, Fluigent developed a technology that makes use of proportional valves. Most pressure controllers require a pressure source which is regulated. Fluigent was the first company to solve this problem by introducing an innovative technology: pressure pumps. What I like most is that you are independent of a computer and can directly control both positive and negative pressure.. Pressure modules (positive pressure, negative pressure, or push-pull modules), microfluidic valve modules, and flow sensors are directly connected to the main platform. Its improved reactivity allows countering, in real-time, the interactions between microfluidic channels in complex situations. Fluigent has developed a pressure-based technology that offers an integrated pressure supply and control (positive and negative pressure) in a light (< 170 g) and compact format (L*l*H = 7*5*4). If you are seeking to replace high-precision syringe pumps or other conventional instruments, we offer modern microfluidic systems and components that enhance productivity.. In the base configuration, the system controls pressure, and the liquid flow is a function of system resistance, fluid viscosity, etc. The compact device stands near the microfluidic device, allowing the user to minimize bench space use without the need of a PC. These can easily be joined together tomatch all application requirementsor reconfigure the system for a new experimental design. Conventional water monitoring is based on laboratory instruments that are generally sophisticated and expensive. Users can output values for custom software applications using theSoftware Development Kit. The delivered software package is suitable for Windows and Linux platforms. It has been designed to maximize versatility with its dual interface USB and RS232 ports and is delivered with a full software package (SDK) to ease integration into Windows or Linux-based software platforms. Instead of looking at the PC, users can keep their eyes on the microscope, adjusting the control dial with one hand. It provides flexibility without compromising performance (accuracy and response time). Configuration 2: 2 pressure modules 2 flow sensors. Our technology is an excellent fit for such applications as it is fully connected and provides excellent fluidic performance while being compact. The algorithm includes a continuous optimization of the parameters that allow it to adapt to the interactions between microfluidic channels in complex situations. These often require more bulky equipment as the internal technology is more advanced. Combine up to 12 modules as your work flow grows. When connected to a computer, one can use our Fluigent software tobenefit from automationorlive monitoring and recording of data. For more information or a technical discussion, 67 avenue de Fontainebleau94 270 Le Kremlin-Bictre, All-in-one pressure supply & pressure/flow control, Advantages of pressure-based microfluidics, Droplet and particle generation in microfluidics. It allows optimal flow control with the reliability required for demanding industrial environments. Support reservoir sizes from 2 mL to one liter laboratory bottles. In this stand-alone configuration, the device allows for pressure or flow rate control and volume dispense making it ideal for benchtop use. The technology is powered by an embedded rechargeable battery to facilitate portability. 2. 67 avenue de Fontainebleau94 270 Le Kremlin-Bictre, All-in-one pressure supply & pressure/flow control, Advantages of pressure-based microfluidics, Droplet and particle generation in microfluidics, Control in real-time, protocol automation, data record and export. Flow-rates can be monitored or controlled using Fluigent DFC self-learning flow rate control algorithm. The MFCS series products are well adapted to the manipulation of fluid volumes in the low to sub microliter per minute range. However, adding such leakage components influence the overall performance: the maximum pressure that can be reached has now decreased of about 15% (from 375 mbar to 310 mbar illustrated in the graph Fig. ThePush-Pullmodules, are available in different pressure and vacuum ranges, to provide the optimum level of pressure control and resolution. Due to its individually stackable channels adapted for different pressures, the PX series allowed for control of the different pressure variations required. This allows the user to set a flow rate directly on the instrument display. The Fluigent LineUp series, including the new push-pull pump, enables precise and highly controlled aspiration and respiration of liquids. The MFCS series product range is the first generation of microfluidic systems. The microfluidic laboratories and industry were struggling to perform their research and develop equipment to the level and precision required in terms of fluid control. Point of care tests such as blood analysis, glucose monitoring, infectious disease testing, cholesterol testing, or cardiac markers are marketed1. There are many advantages to direct control: Configuration 1: 2 pressure modules. 0.1% thanks to our field-proven, patented FASTAB technology allowing optimal flow control with the robustness required in demanding industrial environments. We provide instrument development industrial engineers with the right liquid handling solution for your system. TheLineUpP-SWITCHis a pneumatic valve controller. The technology consists of a uniquely engineered assembly of electronics, sensors integrated with a micropump, and pneumatics to provide high performance.
Connect the outlets of the P-SWITCH to independent reservoirs to perform independent injections. In this stand-alone configuration, the device allows for pressure or flow rate control and volume dispense making it ideal for benchtop use. The LineUp series module can be combined together to add pressure/vacuum channels, valve control and turn one channel into 8 independent outlets using the P-SWITCH. Point of Care (PoC) testing allows one to diagnose diseases at or near the patient site. Combine up to 8 pressure modules on a single F-OEM platform. Each channel can be controlled independently and deliver a specific amount of pressure or vacuum to handle fluids. Single gateway for industrial-grade microfluidic control: The platform can be used to control a pressure source and power other third-party devices required in the microfluidic system. It is available for vacuum and pressures of up to 2 bar. Instead of looking at the PC, users can keep their eyes on the microscope, adjusting the control dial with one hand. For more information or a technical discussion, 67 avenue de Fontainebleau94 270 Le Kremlin-Bictre, All-in-one pressure supply & pressure/flow control, Advantages of pressure-based microfluidics, Droplet and particle generation in microfluidics. It can support a wide range of connections (Wi-Fi, BLE, IoT, USB, industrial bus), and embedded protocols. The set-up allows us to further advance our research in both continuous flow and droplet microfluidics.. ThePRESSURE UNITis a stand-alone sensor forcontinuous measurementof the pressure in a fluidic path. For point-of-care applications, a touch screen can be developed based on your needs. The applied pressure will automatically adjust to maintain the flow rate. Using a pressure leakage or a valve in complement to the pump is a way to circumvent this limitation. In this stand-alone configuration, the device allows for pressure or flow rate control and volume dispense making it ideal for benchtop use. ThePXmodules, are available in different pressure and vacuum ranges, to provide the optimum level of pressure control and resolution. Based on the patented FASTABTM technology, our pressure and flow controllers ensure a stable and pulseless flow to enhance accuracy and reproducibility in the experiments. When using a gas micropump alone, pressure drops are very slow, as shown in Fig. Fluigents i (patent pending) powerful pressure regulation algorithm is based on physical equations and self-learning routines that offer several benefits: By directly connecting a flow rate sensor, it is possible to monitor or control flow rate in real time. Based on our industry leading experience, Fluigent has developed the patented QuadCore pneumatic system, the most advanced microfluidic pumping technology available. Instead of looking at the PC, users can keep their eyes on the microscope, adjusting the control dial with one hand. The MFCS-EX provides up to 8 negative or positive pressure channels to pressurize multiple fluid reservoirs. We offer best-in-class standard & custom OEM components, system development, and engineering services, with strong expertise in fluid management to accelerate your development process. 67 avenue de Fontainebleau94 270 Le Kremlin-Bictre, LineUp Series, the new generation of microfluidic controllers, All-in-one pressure supply & pressure/flow control, Advantages of pressure-based microfluidics, Droplet and particle generation in microfluidics, Dry, oil-free gas, air, any non corrosive or non explosive gas, Aqueous solvent, oil, organic solent, biological sample, Control in real-time, protocol automation, data record and export. When combined with theLINKmodule, the Flow EZcapabilities are extended by using Fluigent software to control the system, or to generate time based protocols and reccord data(OxyGEN software). The FASTAB microfluidic patented technology used by MFCS series avoids cross contamination as there is no direct contact between the instrument and the reagents. Control without a PC using the Push-Pull hardware interface with one hand. Graphically monitor in real-time the pressure measurement using the OxyGEN software. Janire, S., Raquel, C.-C., R_oisn, M. O.
The Push-Pull allows for regulatation of pressure and vacuum down to -800 mbar and up to 1 bar from one single channel. Along with the MCFS-EZ or MCFS-EX, a Manifold can be added to redirect the pressure to multiple fluid reservoirs. Focus on the experiment instead of looking at the PC. The device is well designed and allows for easy control of my microfluidic chips. No flow sensors. Whether your application is with droplets, cell biology, particle studies, or in other research areas, we have the expertise and knowledge to provide the most cost-effective and technically advanced solutions for your fluid control needs. The field-proven technology ensures to obtain quickly reliable and superior results for your experiments. The addition of aFLOW UNITenables one tocontrol or monitor flow rateas well asmeasure a dispensed volume. The Flow EZmodules, are available in different pressure and vacuum ranges, to provide the optimum level of pressure control and resolution. Improved reliability and reproducibility of of results is possible due to the pulseless flow. Support reservoir sizes from 2 mL to one liter laboratory bottles. This allows the user to set a flow rate directly on the instrument display. The addition of aflow sensorenables one tocontrol or monitor flow rateas well asdispense volume. The Flow EZ range of modules allow for regulatation of pressure / vacuum down to -800 mbar and up to 7 bar. Combine up to 12 modules as your work flow grows. The use of pressure to handle fluids also provides a quick response time allowing for precise operations such as stop flow and accurate pressure/flow rate steps. The addition of aFLOW UNITenables one tocontrol or monitor flow rateas well asmeasure a dispensed volume.
The flow generated can be measured or controlled with FLOW UNITs and the Flowboard. Each module is a separate and independant pressure channel. Fig 1: (left) A pressure supply and pressure controller vs our new technology (right) Fluigent engineered technology. Available in two main product line, the LineUpTM series to lead evolutive, compact and adaptable operations and the MFCSTM series for customized and field proven experience. The product line can detect values over the range of-1000 mbar(-15 psi) to7000 mbar(100 psi). 67 avenue de Fontainebleau94 270 Le Kremlin-Bictre, Key indicators to ensure long-term performance of your OEM flow control components, Things you should know when integrating fluidics into your system, DFC, self-learning flow rate control algorithm, Peristaltic pump vs pressure-based microfluidic flow control systems for Organ on-chip applications, Droplet generation using syringe pumps and pressure-based flow controllers, All-in-one pressure supply & pressure/flow control, Advantages of pressure-based microfluidics, Droplet and particle generation in microfluidics, Pressure : 0 to 7000 mbar (101 psi) required pressure supply 7100 mbar (103 psi), Pressure: 0 to 2000 mbar (29 psi) required pressure supply 2100 mbar (30.4 psi) min, 2400 max, Pressure: 0 to 1000 mbar (14.5 psi) required pressure supply 1100 mbar (16 psi) min, 1300 max, Pressure: 0 to 345 mbar (5 psi) required pressure supply 1100 mbar (16 psi) (600 min, 1300 max), Pressure: 0 to 69 mbar (0.9 psi) required pressure supply 150 mbar (2.18 psi), Pressure: 0 to 25 mbar (0.36 psi) required pressure supply 150 mbar (2.18 psi), Vacuum : -25 mbar (-0.36 psi) / -69 mbar (-0.9 psi) / -345 mbar (-5 psi) / -800 mbar required vacuum -800 mbar (-11.6 psi), Push-Pull : -800 mbar (-11.6 psi) to 1000 mbar (14.5 psi) required pressure 1100 mbar (16 psi) min and 1300 max and vacuum -800 mbar (-11.6 psi) (min), 0.1% of full scale CV (on measured values), Liquid flow rate sensor input, customizable to work with third party sensors (through SDK), Control up to 4 x switches or valves per module compatible with Fluigent 2 position switches and rotary valves (M-switch, L-switch, 2-switch), Pressurized or bottled clean dry and non-corrosive or explosive gas (Ambient air, N2, Ar, CO2) (02 could be a thing, need to check), OD 4mm female push in fitting (on standard version, can be fittingless, then it is an M5 thread), >1W groundable for F-OEM platform (can be increased depending on peripherals, eg pump, fans etc) 6W maximum per FEZ module, 48W maximum per SWEZ module (rotary valves ~ 12W), External power, 2A or 7A available from standard, but custom can be accepted using MBPT terminal block connection, USB (standard board), RS232 (alternative board) + other protocols on demand, RJ45 female (or 2wire terminal block for SWEZ lite), 0-24VDC, digital controlled output 5 or 24 volts selectable, 2 x USB2.0 ports (available only on the USB connection protocol version, 0.1 Kg (F-OEM platform), 0.4 Kg (per pressure module with manifold), 0.3 kg (per switch module), Main electronic board. 5 that compares Fluigent solution with a standalone gas micropump. A new generation of point of care diagnostic devices has been recently developed for providing higher sensitivity diagnostics, such as nucleic acid amplification tests.
The Push-Pull can maintain continuous, pulseless flow for days without refilling. With a compact and modular design, the Flow EZ allows you to set and benefit quickly from the pressure-based flow control advantages for your experiments. The use of pressure to handle fluids also provides a quick response time allowing for precise operations such as stop flow and accurate pressure/flow rate steps. Fluigent pressure and flow controllers bring this performance and benefits to the system. Integrated flow control: To switch from pressure control to flow rate control, one can directly add a flow sensor from our industrial FS series to the F-OEM without the need of an additional board. For flow-rate monitoring and control. Point of care devices needing a small footprint can have engineering challenges. The Adapt is used to connect Flow EZ modules with different pressure ranges without the need of additional pressure sources. The PX Pressure-driven flow control simplifies fluid management even for multiple fluids, and reduces the time needed to add or remove channels. A photonic technology institute tests a variety of lab-on-chip systems, the number of flow channels and the required pressures vary from one test to another. Focus on the experiment instead of looking at the PC. It can easily be connected to other microfluidic devices such as FLOW UNIT sensors to allow for flow-rate control. When combined with theLINKmodule, thePush-Pullcapabilities are extended by using Fluigent software to control the system, or to generate time based protocols and reccord data(OxyGEN software). We have a large range of flow sensors ranging from 0-1.5 L/min to 0-5 mL/min. In the base configuration, the system controls pressure or vacuum, and the liquid flow is a function of system resistance, fluid viscosity, etc. See an example of applications using the MFCS series: Separation of parasites from human blood using deterministic lateral displacement, S. H. Holm, J. P. Beech, M. P. Barrett and J. O. Tegenfeldt, Lab Chip, vol.11, 2011. Weighing in less than 170 g and with a volume of 140 cm3, Excellent stability and response time thanks to Fluigent pressure and liquid handling expertise. Using this engineered solution, pressure drop takes less than a second, and the maximum pressure reachable has not deteriorated (see graph). Emerging point of care applications make use of more complex fluidic operations and require compact systems. Combined with Flow EZ and Push-Pull, set a versatile system for pressure-base microfluidic experiments. It provides a dual interface USB and RS232 for high versatility in the integration. Fluigent is an international company which develops, manufactures and supports the most advanced fluid control systems available for microfluidics offering greater control, automation, precision, and ease of use.. Fluigents broad range of solutions for use in microfluidic and nanofluidic applications offer greater control, automation, precision, and ease of use. The PX module is a CE and RoHS compliant single controller available in 3 pressure ranges. This allows to perform operations that require fast response time, or require fast change between applied positive pressure and vacuum. In addition, a microfluidic pressure pump can easily be integrated into a setup with the Software Development Kit (SDK). You can choose the number of channels of the device (4 or 8), each channel range from -800 mbar to 7 bar, and you even have the possibility to integrate a pressure or vacuum source inside the instrument. 3 pressure modules consisting of two 0 2000 mbar and a -800 + 1000 mbar are connected to the main F-OEM board for pressurizing two fluidic reservoirs, allowing for pressure-based fluid handling. Prof. Jeroen Lammertyn, KU Leuven Belgium Biosensors group. Get full control of the setup in a single interface with plug and play capabilities available for all desktop OS, that allows control, monitoring, and automation feature. Our F-OEM offers our highest performance, efficiency, and widest pressure and flow rate ranges to support the most demanding industrial applications, including microfluidic and nanofluidic applications (microchannels, nanochannels, capillaries, lab on a chip). Inject and switch different flow paths. Custom software application: Public SDK libraries are available on GitHub for all integration into the users proprietary software, Adapted to cell culture or other experiments involving resistance variations: the algorithm adjusts its model to the setup resistance in real-time, Save precious sample or reagent: reduced time to reach desired flow rates uses less liquid during a calibration step, Save time with reduced settling time and no calibration. Fig 2: (left) Pneumatic schematic of a standard fluidic system using pressure to move fluids (right) Pneumatic schematic of Fluigent new technology. Fluigent has developed (patent pending) an all-in-one, free standing, compact, integrated pressure-based control with an internal pressure supply technology. By providing two pressure sources (any vacuum or pressurefrom -800 to +2000 mbar), each module is able to deliver one of the two provided pressures through8 independent outlets. Liquid flow rate ranges from a few nL/min to 5 mL/min. It can be used without a PC or controlled with Fluigent Software Solutions to benefit from control in real-time, protocol automation, graphic displays and custom integration. Each module is a separate and independent pressure channel. Customize your own controller to answer your control needs. Each module consists of a separate pressure channel and can be controlled independently. Fluigent industrial builds on our 15 years of pressure-based flow control expertise and proprietary technologies to bring versatile, cost-effective, and customizable OEM products and systems. The technology used in this pressure pumpavoids cross-contaminationbecause liquids only contact air. This system can be integrated, automated or control in real time by using Fluigent Software Solutions.
These can easily be combined tomatch all application requirementsor reconfigure the system for a new experimental design. Valve and switch platform for directing the fluid flow, including bidirectional and rotary multi-port port valves. Excellent response time, pulseless and highly stable, Configurable with pressure and switch control modules, Standalone platform adapted to industrial uses. The FLUIGENT PX pressure controller is a single, miniaturized electronic pressure controller with an integrated and intelligent feedback loop for highest performance. The pressure automatically adjusts in the background to maintain the set flow rate. Output pressures, flow rate, and valves can be controlled by using OxyGEN Fluigent software, or our Software Development Kit (SDK) for custom software applications. Based on our industry leading experience, Fluigent has developed the patented QuadCore pneumatic system, the most advanced microfluidic pumping technology available. With the Fluigent Microfluidic Flow Control System (MFCS-4C) one can sort cells by size, shape and deformability as shown in this publication in the journal Lab-on-a-Chip and explained in the next video. 1186, (2021). The PRESSURE UNIT product line allow for the accurate measurement of pressure and vaccum within the range -1000 mbar to 7 bar. 4 slots for pressure or switch modules. We offer modern microfluidic systems and components that enhance productivity.
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